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The Role of IGF-1 for Fracture Risk in Men

Growth hormone and insulin-like growth factor-1 (IGF-1) are essential for the achievement of normal longitudinal bone growth and bone mass. Preclinical studies using various knockout models have shown that both endocrine (mostly liver-derived) IGF-1 and bone-derived IGF-1 contribute to normal longit...

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Detalhes bibliográficos
Main Authors: Vandenput, Liesbeth, Sjögren, Klara, Svensson, Johan, Ohlsson, Claes
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355958/
https://ncbi.nlm.nih.gov/pubmed/22649422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2012.00051
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