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Triggering of a Dll4–Notch1 loop impairs wound healing in diabetes

Diabetic foot ulcerations (DFUs) represent a major medical, social, and economic problem. Therapeutic options are restricted due to a poor understanding of the pathogenic mechanisms. The Notch pathway plays a pivotal role in cell differentiation, proliferation, and angiogenesis, processes that are p...

詳細記述

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Zheng, Xiaowei, Narayanan, Sampath, Sunkari, Vivekananda Gupta, Eliasson, Sofie, Botusan, Ileana Ruxandra, Grünler, Jacob, Catrina, Anca Irinel, Radtke, Freddy, Xu, Cheng, Zhao, Allan, Ekberg, Neda Rajamand, Lendahl, Urban, Catrina, Sergiu-Bogdan
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452711/
https://ncbi.nlm.nih.gov/pubmed/30886104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1900351116
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