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Protective Effect of the HIF-1A Pro582Ser Polymorphism on Severe Diabetic Retinopathy
OBJECTIVE: Hypoxia is central in the pathogenesis of diabetic retinopathy (DR). Hypoxia-inducible factor-1 (HIF-1) is the key mediator in cellular oxygen homeostasis that facilitates the adaptation to hypoxia. HIF-1 is repressed by hyperglycemia contributing by this to the development of complicatio...
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| Publicado no: | J Diabetes Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535890/ https://ncbi.nlm.nih.gov/pubmed/31214621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2936962 |
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