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Stabilization of HIF-1α is critical to improve wound healing in diabetic mice

Relative hypoxia is essential in wound healing since it normally plays a pivotal role in regulation of all the critical processes involved in tissue repair. Hypoxia-inducible factor (HIF) 1α is the critical transcription factor that regulates adaptive responses to hypoxia. HIF-1α stability and funct...

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Autors principals: Botusan, Ileana Ruxandra, Sunkari, Vivekananda Gupta, Savu, Octavian, Catrina, Anca Irinel, Grünler, Jacob, Lindberg, Stina, Pereira, Teresa, Ylä-Herttuala, Seppo, Poellinger, Lorenz, Brismar, Kerstin, Catrina, Sergiu-Bogdan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614777/
https://ncbi.nlm.nih.gov/pubmed/19057015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805230105
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