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Senescence promotes in vivo reprogramming through p16(INK) (4a) and IL‐6
Cellular senescence is a damage response aimed to orchestrate tissue repair. We have recently reported that cellular senescence, through the paracrine release of interleukin‐6 (IL6) and other soluble factors, strongly favors cellular reprogramming by Oct4, Sox2, Klf4, and c‐Myc (OSKM) in nonsenescen...
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| Veröffentlicht in: | Aging Cell |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5847859/ https://ncbi.nlm.nih.gov/pubmed/29280266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12711 |
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