Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis

Reprogramming of differentiated cells into induced pluripotent stem cells has been recently achieved in vivo in mice. Telomeres are essential for chromosomal stability and determine organismal life span as well as cancer growth. Here, we study whether tissue dedifferentiation induced by in vivo repr...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Marión, Rosa M., López de Silanes, Isabel, Mosteiro, Lluc, Gamache, Benjamin, Abad, María, Guerra, Carmen, Megías, Diego, Serrano, Manuel, Blasco, Maria A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312258/
https://ncbi.nlm.nih.gov/pubmed/28162998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.01.001
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