Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis

Reprogramming of differentiated cells into induced pluripotent stem cells has been recently achieved in vivo in mice. Telomeres are essential for chromosomal stability and determine organismal life span as well as cancer growth. Here, we study whether tissue dedifferentiation induced by in vivo repr...

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Xehetasun bibliografikoak
Argitaratua izan da:Stem Cell Reports
Egile Nagusiak: Marión, Rosa M., López de Silanes, Isabel, Mosteiro, Lluc, Gamache, Benjamin, Abad, María, Guerra, Carmen, Megías, Diego, Serrano, Manuel, Blasco, Maria A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312258/
https://ncbi.nlm.nih.gov/pubmed/28162998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.01.001
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