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TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

TERRAs are long non-coding RNAs generated from the telomeres. Lack of TERRA knockout models has hampered understanding TERRAs’ functions. We recently identified chromosome 20q as one of the main origins of human TERRAs, allowing us to generate the first 20q-TERRA knockout models and to demonstrate t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Montero, Juan J., López-Silanes, Isabel, Megías, Diego, F. Fraga, Mario, Castells-García, Álvaro, Blasco, Maria A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906467/
https://ncbi.nlm.nih.gov/pubmed/29670078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03916-3
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