Chargement en cours...

TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin

TERRAs are long non-coding RNAs generated from the telomeres. Lack of TERRA knockout models has hampered understanding TERRAs’ functions. We recently identified chromosome 20q as one of the main origins of human TERRAs, allowing us to generate the first 20q-TERRA knockout models and to demonstrate t...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Montero, Juan J., López-Silanes, Isabel, Megías, Diego, F. Fraga, Mario, Castells-García, Álvaro, Blasco, Maria A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5906467/
https://ncbi.nlm.nih.gov/pubmed/29670078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03916-3
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!