Role of the polycomb protein Eed in the propagation of repressive histone marks

Polycomb Group (PcG) proteins play an essential role in the epigenetic maintenance of repressive chromatin states. The gene silencing activity of the Polycomb Repressive Complex 2 (PRC2) depends on its ability to tri-methylate lysine 27 of histone H3 (H3K27) via the catalytic SET domain of the EZH2...

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Detalhes bibliográficos
Main Authors: Margueron, Raphael, Justin, Neil, Ohno, Katsuhito, Sharpe, Miriam L, Son, Jinsook, Drury, William J, Voigt, Philipp, Martin, Stephen, Taylor, William R., De Marco, Valeria, Pirrotta, Vincenzo, Reinberg, Danny, Gamblin, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772642/
https://ncbi.nlm.nih.gov/pubmed/19767730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08398
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