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Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis
Polycomb repressive complex 2 (PRC2), a H3K27me3 methyltransferase complex, promotes the development of many organs by silencing ectopic transcription program. However, currently little is known about the role of PRC2 in blood and vascular development. In this study, we interrogated the function of...
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| Veröffentlicht in: | Cell Death Dis |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5477586/ https://ncbi.nlm.nih.gov/pubmed/28406475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.163 |
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