Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis

Polycomb repressive complex 2 (PRC2), a H3K27me3 methyltransferase complex, promotes the development of many organs by silencing ectopic transcription program. However, currently little is known about the role of PRC2 in blood and vascular development. In this study, we interrogated the function of...

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Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: Yu, Wenhua, Zhang, Fang, Wang, Shiyan, Fu, Yi, Chen, Jiahuan, Liang, Xiaodong, Le, Huangying, Pu, William T, Zhang, Bing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
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Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477586/
https://ncbi.nlm.nih.gov/pubmed/28406475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.163
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