Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis

Polycomb repressive complex 2 (PRC2), a H3K27me3 methyltransferase complex, promotes the development of many organs by silencing ectopic transcription program. However, currently little is known about the role of PRC2 in blood and vascular development. In this study, we interrogated the function of...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Yu, Wenhua, Zhang, Fang, Wang, Shiyan, Fu, Yi, Chen, Jiahuan, Liang, Xiaodong, Le, Huangying, Pu, William T, Zhang, Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477586/
https://ncbi.nlm.nih.gov/pubmed/28406475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.163
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