Depletion of polycomb repressive complex 2 core component EED impairs fetal hematopoiesis

Polycomb repressive complex 2 (PRC2), a H3K27me3 methyltransferase complex, promotes the development of many organs by silencing ectopic transcription program. However, currently little is known about the role of PRC2 in blood and vascular development. In this study, we interrogated the function of...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Yu, Wenhua, Zhang, Fang, Wang, Shiyan, Fu, Yi, Chen, Jiahuan, Liang, Xiaodong, Le, Huangying, Pu, William T, Zhang, Bing
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477586/
https://ncbi.nlm.nih.gov/pubmed/28406475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.163
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