TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

Telomere-repeat encoding RNA (referred to as TERRA) has been identified as a potential component of yeast and mammalian telomeres. We show here that TERRA RNA interacts with several telomere-associated proteins, including telomere repeat factors 1 (TRF1) and 2 (TRF2), subunits of the Origin Recognit...

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Main Authors: Deng, Zhong, Norseen, Julie, Wiedmer, Andreas, Riethman, Harold, Lieberman, Paul M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749977/
https://ncbi.nlm.nih.gov/pubmed/19716786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.06.025
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