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TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity
Telomere dysfunction causes chromosomal instability which is associated with many cancers and age-related diseases. The non-coding telomeric repeat-containing RNA (TERRA) forms a structural and regulatory component of the telomere that is implicated in telomere maintenance and chromosomal end protec...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7876106/ https://ncbi.nlm.nih.gov/pubmed/33568696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82406-x |
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