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Mechanism of Intersubunit Ketosynthase-Dehydratase Interaction in Polyketide Synthases
Modular polyketide synthases (PKSs) produce numerous structurally complex natural products with diverse applications in medicine and agriculture. They typically consist of several multienzyme subunits that utilize structurally-defined docking domains (DDs) at their N- and C-termini to ensure correct...
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| Veröffentlicht in: | Nat Chem Biol |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846730/ https://ncbi.nlm.nih.gov/pubmed/29309054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2549 |
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