Encapsulated Cell Technology-Based Delivery of a Complement Inhibitor Reduces Choroidal Neovascularization in a Mouse Model

PURPOSE: Age-related macular degeneration (AMD) is a slowly progressing disease, and risk appears to be tied to an overactive complement system. We have previously demonstrated that mouse choroidal neovascularization (CNV) and smoke-induced ocular pathology can be reduced with an alternative pathway...

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Veröffentlicht in:Transl Vis Sci Technol
Hauptverfasser: Annamalai, Balasubramaniam, Parsons, Nathaniel, Belhaj, Marwa, Brandon, Carlene, Potts, Jay, Rohrer, Bärbel
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2018
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846441/
https://ncbi.nlm.nih.gov/pubmed/29576927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.7.2.3
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