Urinary Mitochondrial DNA Identifies Renal Dysfunction and Mitochondrial Damage in Sepsis-Induced Acute Kidney Injury

BACKGROUND: Recent animal studies have shown that mitochondrial dysfunction initiates and accelerates renal injury in sepsis, but its role in sepsis remains unknown. Mitochondrial stress or dying cells can lead to fragmentation of the mitochondrial genome, which is considered a surrogate marker of m...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Hu, Qiongyuan, Ren, Jianan, Ren, Huajian, Wu, Jie, Wu, Xiuwen, Liu, Song, Wang, Gefei, Gu, Guosheng, Guo, Kun, Li, Jieshou
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846356/
https://ncbi.nlm.nih.gov/pubmed/29682165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8074936
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