Urinary Mitochondrial DNA Identifies Renal Dysfunction and Mitochondrial Damage in Sepsis-Induced Acute Kidney Injury

BACKGROUND: Recent animal studies have shown that mitochondrial dysfunction initiates and accelerates renal injury in sepsis, but its role in sepsis remains unknown. Mitochondrial stress or dying cells can lead to fragmentation of the mitochondrial genome, which is considered a surrogate marker of m...

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Bibliografische gegevens
Gepubliceerd in:Oxid Med Cell Longev
Hoofdauteurs: Hu, Qiongyuan, Ren, Jianan, Ren, Huajian, Wu, Jie, Wu, Xiuwen, Liu, Song, Wang, Gefei, Gu, Guosheng, Guo, Kun, Li, Jieshou
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2018
Onderwerpen:
Clinical Study
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846356/
https://ncbi.nlm.nih.gov/pubmed/29682165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8074936
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