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Released Mitochondrial DNA Following Intestinal Ischemia Reperfusion Induces the Inflammatory Response and Gut Barrier Dysfunction

Ischemia-reperfusion (I/R) injury is a challenging clinical problem, especially injuries involving the gastrointestinal tract. Mitochondrial DNA (mtDNA) is released upon cell death and stress, and can induce the inflammatory response. We aimed to investigate the role of mtDNA in the pathogenesis of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hu, Qiongyuan, Ren, Huajian, Ren, Jianan, Liu, Qinjie, Wu, Jie, Wu, Xiuwen, Li, Guanwei, Wang, Gefei, Gu, Guosheng, Guo, Kun, Hong, Zhiwu, Liu, Song, Li, Jieshou
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943336/
https://ncbi.nlm.nih.gov/pubmed/29743484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25387-8
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