Released Mitochondrial DNA Following Intestinal Ischemia Reperfusion Induces the Inflammatory Response and Gut Barrier Dysfunction

Ischemia-reperfusion (I/R) injury is a challenging clinical problem, especially injuries involving the gastrointestinal tract. Mitochondrial DNA (mtDNA) is released upon cell death and stress, and can induce the inflammatory response. We aimed to investigate the role of mtDNA in the pathogenesis of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Hu, Qiongyuan, Ren, Huajian, Ren, Jianan, Liu, Qinjie, Wu, Jie, Wu, Xiuwen, Li, Guanwei, Wang, Gefei, Gu, Guosheng, Guo, Kun, Hong, Zhiwu, Liu, Song, Li, Jieshou
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943336/
https://ncbi.nlm.nih.gov/pubmed/29743484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25387-8
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