Urinary Mitochondrial DNA Identifies Renal Dysfunction and Mitochondrial Damage in Sepsis-Induced Acute Kidney Injury

BACKGROUND: Recent animal studies have shown that mitochondrial dysfunction initiates and accelerates renal injury in sepsis, but its role in sepsis remains unknown. Mitochondrial stress or dying cells can lead to fragmentation of the mitochondrial genome, which is considered a surrogate marker of m...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Hu, Qiongyuan, Ren, Jianan, Ren, Huajian, Wu, Jie, Wu, Xiuwen, Liu, Song, Wang, Gefei, Gu, Guosheng, Guo, Kun, Li, Jieshou
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
Témata:
Clinical Study
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846356/
https://ncbi.nlm.nih.gov/pubmed/29682165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8074936
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