Urinary Mitochondrial DNA Identifies Renal Dysfunction and Mitochondrial Damage in Sepsis-Induced Acute Kidney Injury

BACKGROUND: Recent animal studies have shown that mitochondrial dysfunction initiates and accelerates renal injury in sepsis, but its role in sepsis remains unknown. Mitochondrial stress or dying cells can lead to fragmentation of the mitochondrial genome, which is considered a surrogate marker of m...

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Bibliografski detalji
Izdano u:Oxid Med Cell Longev
Glavni autori: Hu, Qiongyuan, Ren, Jianan, Ren, Huajian, Wu, Jie, Wu, Xiuwen, Liu, Song, Wang, Gefei, Gu, Guosheng, Guo, Kun, Li, Jieshou
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2018
Teme:
Clinical Study
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846356/
https://ncbi.nlm.nih.gov/pubmed/29682165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8074936
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