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NOS2 polymorphisms in prediction of benefit from first-line chemotherapy in metastatic colorectal cancer patients
BACKGROUND: Macrophages play a crucial role in the interaction between tumor and immune system, and iNOS is known as a surrogate marker of M1 macrophages activation. The goal of the study was to investigate the role of iNOS polymorphisms as prognostic marker in mCRC patients. MATERIALS AND METHODS:...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5844536/ https://ncbi.nlm.nih.gov/pubmed/29522543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193640 |
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