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Single nucleotide polymorphisms in the IGF-IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE-3 trial

The Insulin-like growth factor (IGF)/IGF-receptor pathway with its scaffolding proteins Insulin Receptor Substrate (IRS)1 and IRS2 are crucial regulators of metabolism and progression in metastatic colorectal cancer (mCRC). The goal of the study was the identification of predictive and prognostic ma...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Schirripa, Marta, Zhang, Wu, Heinemann, Volker, Cao, Shu, Okazaki, Satoshi, Yang, Dongyun, Loupakis, Fotios, Berger, Martin D., Ning, Yan, Miyamoto, Yuji, Suenaga, Mitsukuni, Gopez, Roel F., West, Jordan D., Hanna, Diana, Barzi, Afsaneh, Falcone, Alfredo, Stintzing, Sebastian, Lenz, Heinz-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510747/
https://ncbi.nlm.nih.gov/pubmed/28369940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30715
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