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Activation of human smooth muscle BK channels by hydrochlorothiazide requires cell integrity and the presence of BK β(1) subunit
Thiazide-like diuretics are the most commonly used drugs to treat arterial hypertension, with their efficacy being linked to their chronic vasodilatory effect. Previous studies suggest that activation of the large conductance voltage- and Ca(2+)-dependent K(+) (BK) channel (Slo 1, MaxiK channel) is...
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| 出版年: | Acta Pharmacol Sin |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5843832/ https://ncbi.nlm.nih.gov/pubmed/29188803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.133 |
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