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Activation of human smooth muscle BK channels by hydrochlorothiazide requires cell integrity and the presence of BK β(1) subunit
Thiazide-like diuretics are the most commonly used drugs to treat arterial hypertension, with their efficacy being linked to their chronic vasodilatory effect. Previous studies suggest that activation of the large conductance voltage- and Ca(2+)-dependent K(+) (BK) channel (Slo 1, MaxiK channel) is...
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| Publicado no: | Acta Pharmacol Sin |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5843832/ https://ncbi.nlm.nih.gov/pubmed/29188803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.133 |
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