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Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia
BACKGROUND: Degeneration of cone photoreceptors leads to loss of vision in patients suffering from age-related macular degeneration (AMD) and other cone dystrophies. Evidence, such as choroidal ischemia and decreased choroidal blood flow, implicates reduced tissue oxygenation in AMD pathology and su...
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| Publicado no: | Mol Neurodegener |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842520/ https://ncbi.nlm.nih.gov/pubmed/29514656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0243-y |
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