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Elovl4 5-bp deletion does not accelerate cone photoreceptor degeneration in an all-cone mouse

Mutations in the elongation of very long chain fatty acid 4 (ELOVL4) gene cause Stargardt macular dystrophy 3 (STGD3), a rare, juvenile-onset, autosomal dominant form of macular degeneration. Although several mouse models have already been generated to investigate the link between the three identifi...

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Publicado en:PLoS One
Autores principales: Schori, Christian, Agbaga, Martin-Paul, Brush, Richard S., Ayyagari, Radha, Grimm, Christian, Samardzija, Marijana
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5749830/
https://ncbi.nlm.nih.gov/pubmed/29293603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190514
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