Elovl4 5-bp deletion knock-in mouse model for Stargardt-like macular degeneration demonstrates accumulation of ELOVL4 and lipofuscin

The mechanism underlying photoreceptor degeneration in autosomal dominant Stargardt like macular degeneration (STGD3) due to mutations in the elongation of very long chain fatty acids-4 (ELOVL4) gene is not fully understood. To evaluate the pathological events associated with STGD3, we used a mouse...

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Bibliographic Details
Main Authors: Vasireddy, Vidyullatha, Jablonski, Monica M., Khan, Naheed W., Wang, Xiao Fei, Sahu, Priya, Sparrow, Janet R, Ayyagari, Radha
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783393/
https://ncbi.nlm.nih.gov/pubmed/19682985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2009.07.021
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