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Elovl4 5-bp deletion knock-in mouse model for Stargardt-like macular degeneration demonstrates accumulation of ELOVL4 and lipofuscin
The mechanism underlying photoreceptor degeneration in autosomal dominant Stargardt like macular degeneration (STGD3) due to mutations in the elongation of very long chain fatty acids-4 (ELOVL4) gene is not fully understood. To evaluate the pathological events associated with STGD3, we used a mouse...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783393/ https://ncbi.nlm.nih.gov/pubmed/19682985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2009.07.021 |
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