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Hif1a and Hif2a can be safely inactivated in cone photoreceptors

Impaired tissue oxygenation results in hypoxia and leads to the activation of hypoxia-inducible transcription factors (HIF). A chronic, HIF-triggered molecular response to hypoxia may be an important factor in the etiology of age-related macular degeneration (AMD) and is likely activated before any...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Samardzija, Marijana, Barben, Maya, Todorova, Vyara, Klee, Katrin, Storti, Federica, Grimm, Christian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834587/
https://ncbi.nlm.nih.gov/pubmed/31695081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52508-8
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