Digoxin-induced retinal degeneration depends on rhodopsin

Na,K-ATPases are energy consuming ion pumps that are required for maintaining ion homeostasis in most cells. In the retina, Na,K-ATPases are especially important to sustain the dark current in photoreceptor cells needed for rapid hyperpolarization of rods and cones in light. Cardiac glycosides like...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Landfried, Britta, Samardzija, Marijana, Barben, Maya, Schori, Christian, Klee, Katrin, Storti, Federica, Grimm, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386584/
https://ncbi.nlm.nih.gov/pubmed/28300845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.94
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