Alpha‐defensins (α‐Defs) in Crohn's disease: decrease of ileal α‐Def 5 via permanent methylation and increase in plasma α‐Def 1‐3 concentrations offering biomarker utility

An impaired expression of α‐defensins (α‐Defs) in the ileal mucosa and, conversely, increased levels in plasma, have been reported in Crohn's disease (CD). However, the specificity and correlation of these findings with the degree of inflammation are unclear. We aimed to characterize the concen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Exp Immunol
Prif Awduron: Cerrillo, E., Moret, I., Iborra, M., Ramos, D., Busó, E., Tortosa, L., Sáez‐González, E., Nos, P., Beltrán, B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842403/
https://ncbi.nlm.nih.gov/pubmed/29193023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13085
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