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Alpha‐defensins (α‐Defs) in Crohn's disease: decrease of ileal α‐Def 5 via permanent methylation and increase in plasma α‐Def 1‐3 concentrations offering biomarker utility

An impaired expression of α‐defensins (α‐Defs) in the ileal mucosa and, conversely, increased levels in plasma, have been reported in Crohn's disease (CD). However, the specificity and correlation of these findings with the degree of inflammation are unclear. We aimed to characterize the concen...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Cerrillo, E., Moret, I., Iborra, M., Ramos, D., Busó, E., Tortosa, L., Sáez‐González, E., Nos, P., Beltrán, B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842403/
https://ncbi.nlm.nih.gov/pubmed/29193023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13085
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