Alpha‐defensins (α‐Defs) in Crohn's disease: decrease of ileal α‐Def 5 via permanent methylation and increase in plasma α‐Def 1‐3 concentrations offering biomarker utility

An impaired expression of α‐defensins (α‐Defs) in the ileal mucosa and, conversely, increased levels in plasma, have been reported in Crohn's disease (CD). However, the specificity and correlation of these findings with the degree of inflammation are unclear. We aimed to characterize the concen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Exp Immunol
Päätekijät: Cerrillo, E., Moret, I., Iborra, M., Ramos, D., Busó, E., Tortosa, L., Sáez‐González, E., Nos, P., Beltrán, B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842403/
https://ncbi.nlm.nih.gov/pubmed/29193023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13085
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