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Alpha‐defensins (α‐Defs) in Crohn's disease: decrease of ileal α‐Def 5 via permanent methylation and increase in plasma α‐Def 1‐3 concentrations offering biomarker utility

An impaired expression of α‐defensins (α‐Defs) in the ileal mucosa and, conversely, increased levels in plasma, have been reported in Crohn's disease (CD). However, the specificity and correlation of these findings with the degree of inflammation are unclear. We aimed to characterize the concen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Exp Immunol
Egile Nagusiak: Cerrillo, E., Moret, I., Iborra, M., Ramos, D., Busó, E., Tortosa, L., Sáez‐González, E., Nos, P., Beltrán, B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5842403/
https://ncbi.nlm.nih.gov/pubmed/29193023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13085
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