Guanylate cyclase 2C agonism corrects CFTR mutants

Cystic fibrosis (CF) is a genetic disorder in which epithelium-generated fluid flow from the lung, intestine, and pancreas is impaired due to mutations disrupting CF transmembrane conductance regulator (CFTR) channel function. CF manifestations of the pancreas and lung are present in the vast majori...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Arora, Kavisha, Huang, Yunjie, Mun, Kyushik, Yarlagadda, Sunitha, Sundaram, Nambirajan, Kessler, Marco M., Hannig, Gerhard, Kurtz, Caroline B., Silos-Santiago, Inmaculada, Helmrath, Michael, Palermo, Joseph J., Clancy, John P., Steinbrecher, Kris A., Naren, Anjaparavanda P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841874/
https://ncbi.nlm.nih.gov/pubmed/28978796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93686
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky