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IRE1α deficiency promotes tumor cell death and eIF2α degradation through PERK dipendent autophagy
Sensors of endoplasmic reticulum (ER) stress function in a co-ordinated manner. In the present study we investigated the relationship between IRE1α and PERK pathways and survival of ER stressed U937 cells and BC3 cells. To this end, we investigated the effects of a subcytotoxic concentration of Tuni...
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| 出版年: | Cell Death Discov |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841272/ https://ncbi.nlm.nih.gov/pubmed/29531800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-017-0002-9 |
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