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Regulation of Autophagy Via PERK-eIF2α Effectively Relieve the Radiation Myelitis Induced by Iodine-125

Radiation myelitis is the most serious complication in clinical radiotherapy for spinal metastases. We previously showed that (125)I brachytherapy induced apoptosis of spinal cord neurons accompanied by autophagy. In this study, we further investigated the mechanism by which (125)I radiation trigger...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Yang, Zuozhang, Xu, Yongqing, Xu, Lei, Maccauro, Giulio, Rossi, Barbara, Chen, Yanjin, Li, Hongjun, Zhang, Jing, Sun, Hongpu, Yang, Yihao, Xu, Da, Liu, Xuefeng
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3818370/
https://ncbi.nlm.nih.gov/pubmed/24223705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076819
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