Regulation of Autophagy Via PERK-eIF2α Effectively Relieve the Radiation Myelitis Induced by Iodine-125

Radiation myelitis is the most serious complication in clinical radiotherapy for spinal metastases. We previously showed that (125)I brachytherapy induced apoptosis of spinal cord neurons accompanied by autophagy. In this study, we further investigated the mechanism by which (125)I radiation trigger...

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Bibliografiske detaljer
Main Authors:	Yang, Zuozhang, Xu, Yongqing, Xu, Lei, Maccauro, Giulio, Rossi, Barbara, Chen, Yanjin, Li, Hongjun, Zhang, Jing, Sun, Hongpu, Yang, Yihao, Xu, Da, Liu, Xuefeng
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science 2013
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3818370/ https://ncbi.nlm.nih.gov/pubmed/24223705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076819
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Regulation of Autophagy Via PERK-eIF2α Effectively Relieve the Radiation Myelitis Induced by Iodine-125

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