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IRE1α deficiency promotes tumor cell death and eIF2α degradation through PERK dipendent autophagy
Sensors of endoplasmic reticulum (ER) stress function in a co-ordinated manner. In the present study we investigated the relationship between IRE1α and PERK pathways and survival of ER stressed U937 cells and BC3 cells. To this end, we investigated the effects of a subcytotoxic concentration of Tuni...
Shranjeno v:
| izdano v: | Cell Death Discov |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841272/ https://ncbi.nlm.nih.gov/pubmed/29531800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-017-0002-9 |
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