טוען...
Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade
Rheb, a ubiquitous small GTPase, is well known to bind and activate mTOR, which augments protein synthesis. Inhibition of protein synthesis is also physiologically regulated. Thus, with cell stress the unfolded protein response system leads to phosphorylation of the initiation factor eIF2α and arres...
שמור ב:
הוצא לאור ב: | Cell Rep |
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Main Authors: | , , , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
2015
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4524804/ https://ncbi.nlm.nih.gov/pubmed/25660019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.01.014 |
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