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Forebrain Depletion of Rheb Elicits Spatial Memory Deficits in Mice
The precise molecular and cellular events responsible for age-dependent cognitive dysfunctions remain unclear. We report that small guanine nucleotide-binding protein Rheb (ras homolog enriched in brain), an activator of mammalian target of rapamycin (mTOR), regulates memory functions in mice. Condi...
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| 發表在: | Neurobiol Aging |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5209246/ https://ncbi.nlm.nih.gov/pubmed/27960107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.11.006 |
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