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IRE1α deficiency promotes tumor cell death and eIF2α degradation through PERK dipendent autophagy

Sensors of endoplasmic reticulum (ER) stress function in a co-ordinated manner. In the present study we investigated the relationship between IRE1α and PERK pathways and survival of ER stressed U937 cells and BC3 cells. To this end, we investigated the effects of a subcytotoxic concentration of Tuni...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Death Discov
Asıl Yazarlar: Storniolo, Antonello, Alfano, Vincenzo, Carbotta, Sabino, Ferretti, Elisabetta, Di Renzo, Livia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841272/
https://ncbi.nlm.nih.gov/pubmed/29531800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-017-0002-9
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