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Arrestins: Critical Players in Trafficking of Many GPCRs()
Arrestins specifically bind active phosphorylated G protein-coupled receptors (GPCRs). Receptor binding induces the release of the arrestin C-tail, which in non-visual arrestins contains high-affinity binding sites for clathrin and its adaptor AP2. Thus, serving as a physical link between the recept...
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| Publicat a: | Prog Mol Biol Transl Sci |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841159/ https://ncbi.nlm.nih.gov/pubmed/26055052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2015.02.010 |
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