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Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis

Bioenergetic failure and oxidative stress are common pathological hallmarks of amyotrophic lateral sclerosis (ALS), but whether these could be targeted effectively for novel therapeutic intervention needs to be determined. One of the reported contributors to ALS pathology is mitochondrial dysfunctio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Mol Med
Egile Nagusiak: Joshi, Amit U, Saw, Nay L, Vogel, Hannes, Cunnigham, Anna D, Shamloo, Mehrdad, Mochly‐Rosen, Daria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840540/
https://ncbi.nlm.nih.gov/pubmed/29335339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708166
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