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Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis

Bioenergetic failure and oxidative stress are common pathological hallmarks of amyotrophic lateral sclerosis (ALS), but whether these could be targeted effectively for novel therapeutic intervention needs to be determined. One of the reported contributors to ALS pathology is mitochondrial dysfunctio...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Joshi, Amit U, Saw, Nay L, Vogel, Hannes, Cunnigham, Anna D, Shamloo, Mehrdad, Mochly‐Rosen, Daria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5840540/
https://ncbi.nlm.nih.gov/pubmed/29335339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708166
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