Potential biomarkers to follow the progression and treatment response of Huntington’s disease

Huntington’s disease (HD) is a rare genetic disease caused by expanded polyglutamine repeats in the huntingtin protein resulting in selective neuronal loss. Although genetic testing readily identifies those who will be affected, current pharmacological treatments do not prevent or slow down disease...

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Bibliografski detalji
Izdano u:J Exp Med
Glavni autori: Disatnik, Marie-Hélène, Joshi, Amit U., Saw, Nay L., Shamloo, Mehrdad, Leavitt, Blair R., Qi, Xin, Mochly-Rosen, Daria
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2016
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110026/
https://ncbi.nlm.nih.gov/pubmed/27821553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160776
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