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The challenge in translating basic research discoveries to treatment of Huntington disease
Huntington disease is a rare neurodegenerative disease resulting from insertion and/or expansion of a polyglutamine repeats close to the N-terminal of the huntingtin protein. Although unequivocal genetic tests have been available for about 20 years, current pharmacological treatments do not prevent...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4091548/ https://ncbi.nlm.nih.gov/pubmed/25054095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rdis.28637 |
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