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Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington’s disease
Mitochondrial dysfunction is implicated in multiple neurodegenerative diseases. In order to maintain a healthy population of functional mitochondria in cells, defective mitochondria must be properly eliminated by lysosomal machinery in a process referred to as mitophagy. Here, we uncover a new molec...
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| Publicado no: | EMBO Mol Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604685/ https://ncbi.nlm.nih.gov/pubmed/26268247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505256 |
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