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Potential biomarkers to follow the progression and treatment response of Huntington’s disease

Huntington’s disease (HD) is a rare genetic disease caused by expanded polyglutamine repeats in the huntingtin protein resulting in selective neuronal loss. Although genetic testing readily identifies those who will be affected, current pharmacological treatments do not prevent or slow down disease...

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Detalles Bibliográficos
Publicado en:J Exp Med
Main Authors: Disatnik, Marie-Hélène, Joshi, Amit U., Saw, Nay L., Shamloo, Mehrdad, Leavitt, Blair R., Qi, Xin, Mochly-Rosen, Daria
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110026/
https://ncbi.nlm.nih.gov/pubmed/27821553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160776
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