Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection: The TANGO I Randomized Clinical Trial

IMPORTANCE: Meropenem-vaborbactam is a combination carbapenem/beta-lactamase inhibitor and a potential treatment for severe drug-resistant gram-negative infections. OBJECTIVE: To evaluate efficacy and adverse events of meropenem-vaborbactam in complicated urinary tract infection (UTI), including acu...

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Bibliografiske detaljer
Udgivet i:JAMA
Main Authors: Kaye, Keith S., Bhowmick, Tanaya, Metallidis, Symeon, Bleasdale, Susan C., Sagan, Olexiy S., Stus, Viktor, Vazquez, Jose, Zaitsev, Valerii, Bidair, Mohamed, Chorvat, Erik, Dragoescu, Petru Octavian, Fedosiuk, Elena, Horcajada, Juan P., Murta, Claudia, Sarychev, Yaroslav, Stoev, Ventsislav, Morgan, Elizabeth, Fusaro, Karen, Griffith, David, Lomovskaya, Olga, Alexander, Elizabeth L., Loutit, Jeffery, Dudley, Michael N., Giamarellos-Bourboulis, Evangelos J.
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2018
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838656/
https://ncbi.nlm.nih.gov/pubmed/29486041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.0438
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