Effect of Meropenem-Vaborbactam vs Piperacillin-Tazobactam on Clinical Cure or Improvement and Microbial Eradication in Complicated Urinary Tract Infection: The TANGO I Randomized Clinical Trial

IMPORTANCE: Meropenem-vaborbactam is a combination carbapenem/beta-lactamase inhibitor and a potential treatment for severe drug-resistant gram-negative infections. OBJECTIVE: To evaluate efficacy and adverse events of meropenem-vaborbactam in complicated urinary tract infection (UTI), including acu...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Kaye, Keith S., Bhowmick, Tanaya, Metallidis, Symeon, Bleasdale, Susan C., Sagan, Olexiy S., Stus, Viktor, Vazquez, Jose, Zaitsev, Valerii, Bidair, Mohamed, Chorvat, Erik, Dragoescu, Petru Octavian, Fedosiuk, Elena, Horcajada, Juan P., Murta, Claudia, Sarychev, Yaroslav, Stoev, Ventsislav, Morgan, Elizabeth, Fusaro, Karen, Griffith, David, Lomovskaya, Olga, Alexander, Elizabeth L., Loutit, Jeffery, Dudley, Michael N., Giamarellos-Bourboulis, Evangelos J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838656/
https://ncbi.nlm.nih.gov/pubmed/29486041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2018.0438
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