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Biochemical Activity of Vaborbactam
The most common mechanism of resistance to β-lactams antibiotics in Gram-negative bacteria is production of β-lactamase enzymes capable of cleaving the β-lactam ring. Inhibition of β-lactamase activity with small-molecule drugs is a proven strategy to restore the potency of many β-lactam antibiotics...
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| 發表在: | Antimicrob Agents Chemother |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985712/ https://ncbi.nlm.nih.gov/pubmed/31712199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01935-19 |
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